Purpose: NSF’s SBIR and STTR programs provide non-dilutive funds for early-stage research and development (R&D) at small businesses. This R&D should be based on innovative, transformational technology with potential for substantial commercial and/or societal benefits. The programs invite proposals from small businesses across a broad range of science and engineering disciplines. For the STTR program, this must be in collaboration with researchers at universities, Federally-Funded Research and Development Centers, and other non-profit institutions.

Application Due Dates:
SBIR Phase I Proposal: June 16, 2016
STTR Phase I Proposal: June 20, 2016

Budget: $225,000 for a 6-12 month development/ feasibility project. You can then compete for a second grant of up to $750,000 over a 2 year period, with the aim of advancing the technology toward commercial deployment.


Selected Topics:

Biological Technologies (BT)

  • BT3. Life Sciences Research Tools
  • BT4. Bioinstrumentation
  • BT7. Computational Biology and Bioinformatics
  • BT8. Advanced Biomanufacturing- New Topic
  • BT9. Advanced technologies for functional genomics in organismal systems – New Topic
  • Tissue Engineering and Regenerative Medicine

Smart Health (SH) and Biomedical (BM) Technologies

  • SH1. Business Models for User-Centered Healthcare
  • SH2. Digital Health Information Infrastructure
  • SH3. From Data to Decisions
  • SH4. Interoperability of Health Record Systems, Medical Sensors, Devices and Robotics
  • BM1. Pharmaceutical Manufacturing
  • BM2. Materials for Biomedical Applications
  • BM3. Biomedical Engineering
  • BM4. Noninvasive Imaging of Brain Function
  • BM5. Medical Imaging Technologies
  • BM6. Diagnostic Assays and Platforms
  • BM7. Drug Delivery


View the SBIR Phase I Solicitation
View the STTR Phase I Solicitation


To discuss these opportunities or to learn about other non-dilutive funding that may be relevant to your organization, send us a note and we’ll get in touch with you directly!

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